Professor Andrew Lloyd is an infectious diseases physician, and an epidemiology, virology and immunology researcher. He is an NHMRC Practitioner Fellow. He is the Head of the Viral Immunology Systems Program (VISP) in the Kirby Institute, and Director of the UNSW Fatigue Clinic and Research Program at the University of NSW. He also provides clinical services in infectious diseases at Prince of Wales Hospital, and hepatology services to Justice Health in the NSW prisons. His research program has been continuously funded by NHMRC since 1993.
The broad goal of his research is to better understand the host and pathogen determinants of infectious diseases outcomes. The laboratory-based research aims to understand the cellular and molecular basis of the pathogenesis of human RNA viral infections, particularly hepatitis C, dengue and SARS CoV-2 infections. The scope of the research extends from laboratory studies of the basic biology of the virus and host contributors to disease pathogenesis. The studies are based on cutting edge cellular and molecular assay techniques including next generation sequencing of viruses, multi-colour flow cytometry to characterise virus-specific B and T cell responses, neutralisation assays, enzyme-linked immunospot (ELISpot) and mutliplex cytokine detection assays, as well as high throughput transcriptomics.
The clinical aspects of his research program are focused firstly on the prison context where chronic viral hepatitis is prevalent, The research includes cohort studies and implementation studies exploring hepatitis C and its treatment in the prison setting. Secondly the clinical research program is focused on the epidemiology, pathogenesis and management of post-infective fatigue states, including following Epstein-Barr virus (EBV), Ross River virus (RRV), Q fever infections, and SARS CoV-2 infections.
Broad Research Areas:
Immunology, Virology, Infectious Diseases, Inflammation
MB BS Syd, PhD UNSW, FRACP, FAHMS
Society Memberships & Professional Activities:
American Association of Immunologists; Australasian Society for Infectious Diseases; Australasian Society for Immunology; Australasian Society for HIV Medicine; Australian Centre for HIV and Hepatitis Virology (ACH2)
Specific Research Keywords:
Hepatitis C, anti-viral immunity, T cells, B cells, cytokines, post-infective fatigue states