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Lecturer

Dr Melanie Walker

Viral Immunology Systems Program
Phone
83180024
E-mail
melanie.walker@unsw.edu.au
Location
WW Lv5 532 E
Wijaya R; Stoddart J; Adhikari A; Abayasingam A; Bartlett AW; Rawlinson W; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Martinello M; Lloyd AR; Tedla N; Bull RA; Walker MR, 2026, 'C3d Complement Activation and Antibody Immunity in Convalescent COVID-19: Insights From Adults and Children', Journal of Immunology Research, 2026, http://dx.doi.org/10.1155/jimr/7429749
2026
Dalgaard N; Olsen RW; Adams Y; Mendez BL; Rudbaek JJ; Bisholm SAG; Mousiliou A; Walker MR; Hviid L; Tahar R; Ndam NT; Barfod L; Jensen AR, 2025, 'A monoclonal antibody selectively recognizing PfEMP1 proteins associated with cerebral malaria', Scientific Reports, 15, http://dx.doi.org/10.1038/s41598-025-18465-1
2025
Walker MR; Leung P; Keoshkerian E; Pirozyan MR; Lloyd A; Luciani F; Bull RA, 2025, 'Temporal dynamics of viral fitness and the adaptive immune response in HCV infection', , 13, http://dx.doi.org/10.7554/elife.102232.3
2025
Walker MR; Leung P; Keoshkerian E; Pirozyan MR; Lloyd A; Luciani F; Bull RA, 2025, 'Temporal dynamics of viral fitness and the adaptive immune response in HCV infection', , 13, pp. rp102232, http://dx.doi.org/10.7554/elife.102232
2025
Jamali E; Quadeer AA; Tedla N; McKay MR; Lloyd A; Walker MR; Bull RA, 2025, 'Anti-HCV antibodies: A battle for breadth and potency', Antiviral Research, 238, http://dx.doi.org/10.1016/j.antiviral.2025.106165
2025
Bassi MR; Cristinoi B; Buitenwerf F; Cuadrado MB; Björnsson KH; Walker MR; Partey FD; Ward AB; Ofori MF; Barfod L, 2025, 'Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host', Plos Pathogens, 21, http://dx.doi.org/10.1371/journal.ppat.1013107
2025
Partey FD; Dowuona JNN; Pobee ANA; Walker MR; Aculley B; Prah DA; Ofori MF; Barfod LK, 2024, 'Atypical memory B cell frequency correlates with antibody breadth and function in malaria immune adults', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-55206-2
2024
Harney BL; Sacks-Davis R; Agius P; van Santen DK; Traeger MW; Wilkinson AL; Asselin J; Fairley CK; Roth N; Bloch M; Matthews GV; Donovan B; Guy R; Stoové M; Hellard ME; Doyle JS; Aung HL; Baillie G; Bastian L; Bateson D; Boyd M; Carter A; Cogle A; Costello J; Dimech W; El-Hayek C; Ellard J; Franklin L; Hocking J; Kim J; Nguyen L; Nguyen T; Nolan D; O’Connor C; Patel P; Pendle S; Polkinghorne V; Reed P; Ryder N; Selvey C; Walker M; Watson N, 2024, 'Risk of Primary Incident Hepatitis C Infection Following Bacterial Sexually Transmissible Infections Among Gay and Bisexual Men in Australia From 2016 to 2020', Open Forum Infectious Diseases, 11, http://dx.doi.org/10.1093/ofid/ofae099
2024
Walker MR; Underwood A; Björnsson KH; Raghavan SSR; Bassi MR; Binderup A; Pham LV; Ramirez S; Pinholt M; Dagil R; Knudsen AS; Idorn M; Soegaard M; Wang K; Ward AB; Salanti A; Bukh J; Barfod L, 2024, 'Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages', Communications Biology, 7, http://dx.doi.org/10.1038/s42003-024-06951-7
2024
Underwood AP; Gupta M; Wu BR; Eltahla AA; Boo I; Wang JJ; Agapiou D; Abayasingam A; Reynaldi A; Keoshkerian E; Zhao Y; Brasher N; Walker MR; Bukh J; Maher L; Gordon T; Davenport MP; Luciani F; Drummer HE; Lloyd AR; Bull RA, 2024, 'B-cell characteristics define HCV reinfection outcome', Journal of Hepatology, 81, pp. 415 - 428, http://dx.doi.org/10.1016/j.jhep.2024.04.004
2024
Underwood AP; Gupta M; Wu B-R; Eltahla AA; Boo I; Wang JJ; Agapiou D; Abayasingam A; Reynaldi A; Keoshkerian E; Zhao Y; Brasher N; Walker MR; Bukh J; Maher L; Gordon T; Davenport M; Luciani F; Drummer HE; Lloyd AR; Bull RA, 2023, 'B Cell Signatures and Antibody Imprinting Define HCV Reinfection Outcome', , http://dx.doi.org/10.2139/ssrn.4418620
2023
Walker MR; Idorn M; Bennett A; Søgaard M; Salanti A; Ditlev SB; Barfod L, 2023, 'Characterization of SARS-CoV-2 humoral immune response in a subject with unique sampling: A case report', Immunity Inflammation and Disease, 11, http://dx.doi.org/10.1002/iid3.910
2023
Heron JE; McManus H; Vickers T; Ryan K; Wright E; Carter A; Stoove M; Asselin J; Grulich A; Donovan B; Guy R; Varma R; Chen M; Ryder N; Lewis DA; Templeton DJ; O’Connor CC; Gracey DM; Bastian L; Bateson D; Bowden S; Boyd M; Callander D; Aung HL; Cogle A; Costello J; Dimech W; Dittmer J; El-Hayek C; Ellard J; Fairley C; Franklin L; Hellard M; Hocking J; Kim J; McGill S; Nolan D; Patel P; Pendle S; Polkinghorne V; Nguyen L; Nguyen T; Reed P; Roth N; Selvey C; Traeger M; Walker M; West M, 2023, 'Renal impairment associated with tenofovir disoproxil fumarate for antiretroviral therapy and HIV pre-exposure prophylaxis: An observational cohort study', Plos One, 18, http://dx.doi.org/10.1371/journal.pone.0280339
2023
Kaptoge S; Seshasai SRK; Sun L; Walker M; Bolton T; Spackman S; Ataklte F; Willeit P; Bell S; Burgess S; Pennells L; Altay S; Assmann G; Ben-Shlomo Y; Best LG; Björkelund C; Blazer DG; Brenner H; Brunner EJ; Dagenais GR; Cooper JA; Cooper C; Crespo CJ; Cushman M; D'Agostino RB; Daimon M; Daniels LB; Danker R; Davidson KW; de Jongh RT; Donfrancesco C; Ducimetiere P; Elders PJM; Engström G; Ford I; Gallacher I; Bakker SJL; Goldbourt U; de La Cámara G; Grimsgaard S; Gudnason V; Hansson PO; Imano H; Jukema JW; Kabrhel C; Kauhanen J; Kavousi M; Kiechl S; Knuiman MW; Kromhout D; Krumholz HM; Kuller LH; Laatikainen T; Lowler DA; Meyer HE; Mukamal K; Nietert PJ; Ninomiya T; Nitsch D; Nordestgaard BG; Palmieri L; Price JF; Ridker PM; Sun Q; Rosengren A; Roussel R; Sakurai M; Salomaa V; Schöttker B; Shaw JE; Strandberg TE; Sundström J; Tolonen H; Tverdal A; Verschuren WMM; Völzke H; Wagenknecht L; Wallace RB; Wannamethee SG; Wareham NJ; Wassertheil-Smoller S; Yamagishi K; Yeap BB; Harrison S; Inouye M; Griffin S; Butterworth AS; Wood AM; Thompson SG; Sattar N; Danesh J; Di Angelantonio E; Tipping RW; Russell S; Johansen M; Bancks MP; Mongraw-Chaffin M; Magliano D; Barr ELM; Zimmet PZ, 2023, 'Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation', Lancet Diabetes and Endocrinology, 11, pp. 731 - 742, http://dx.doi.org/10.1016/S2213-8587(23)00223-1
2023
Knudsen AS; Walker MR; Agullet JP; Björnsson KH; Bassi MR; Barfod L, 2022, 'Enhancing neutralization of Plasmodium falciparum using a novel monoclonal antibody against the rhoptry-associated membrane antigen', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-06921-1
2022
Walker MR; Podlekareva D; Johnsen S; Leerhøy B; Fougeroux C; Søgaard M; Salanti A; Ditlev SB; Barfod L, 2022, 'SARS-CoV-2 RBD-Specific Antibodies Induced Early in the Pandemic by Natural Infection and Vaccination Display Cross-Variant Binding and Inhibition', Viruses, 14, http://dx.doi.org/10.3390/v14091861
2022
Traeger MW; Guy R; Asselin J; Patel P; Carter A; Wright EJ; Grulich A; McManus H; Fairley CK; Chow EPF; McNulty A; Finlayson R; Bell C; Owen L; Marshall L; Russell D; O'Donnell D; Donovan B; Hellard ME; Stoové MA; Bastian L; Bateson D; Bowden S; Boyd M; Callander D; Cogle A; Costello J; Dimech W; Dittmer J; El-Hayek C; Ellard J; Franklin L; Hocking J; Kim J; McGill S; Nolan D; Pendle S; Polkinghorne V; Nguyen L; Nguyen T; O'Connor C; Reed P; Roth N; Ryder N; Selvey C; Stoové M; Vickers T; Walker M; Watchirs-Smith L; West M, 2022, 'Real-world trends in incidence of bacterial sexually transmissible infections among gay and bisexual men using HIV pre-exposure prophylaxis (PrEP) in Australia following nationwide PrEP implementation: an analysis of sentinel surveillance data', Lancet Infectious Diseases, 22, pp. 1231 - 1241, http://dx.doi.org/10.1016/S1473-3099(22)00175-X
2022
Knudsen AS; Björnsson KH; Bassi MR; Walker MR; Kok A; Cristinoi B; Jensen AR; Barfod L, 2021, 'Strain-Dependent Inhibition of Erythrocyte Invasion by Monoclonal Antibodies Against Plasmodium falciparum CyRPA', Frontiers in Immunology, 12, http://dx.doi.org/10.3389/fimmu.2021.716305
2021
Brasher NA; Eltahla AA; Underwood A; Boo I; Rizzetto S; Walker MR; Rodrigo C; Luciani F; Maher L; Drummer HE; Tedla N; Lloyd AR; Bull RA, 2020, 'B cell immunodominance in primary hepatitis C virus infection', Journal of Hepatology, 72, pp. 670 - 679, http://dx.doi.org/10.1016/j.jhep.2019.11.011
2020
Walker MR; Knudsen AS; Partey FD; Bassi MR; Frank AM; Castberg FC; Sarbah EW; Ofori MF; Hviid L; Barfod L, 2020, 'Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children', Plos One, 15, http://dx.doi.org/10.1371/journal.pone.0243943
2020
Mina M; Underwood A; Eltahla A; Wu BR; Walker MR; Bull RA; Lloyd AR, 2020, 'Anti-envelope antibody responses in highly exposed seronegative individuals may be associated with protection from HCV infection', Journal of Viral Hepatitis, 27, pp. 1012 - 1021, http://dx.doi.org/10.1111/jvh.13339
2020
Walker MR; Eltahla AA; Mina MM; Li H; Lloyd AR; Bull RA, 2020, 'Envelope-specific IgG3 and IgG1 responses are associated with clearance of acute hepatitis C virus infection', Viruses, 12, pp. 75, http://dx.doi.org/10.3390/v12010075
2020
Walker MR; Leung P; Eltahla AA; Underwood A; Abayasingam A; Brasher NA; Li H; Wu BR; Maher L; Luciani F; Lloyd AR; Bull RA, 2019, 'Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies', Scientific Reports, 9, pp. 13300, http://dx.doi.org/10.1038/s41598-019-49454-w
2019
Wu BR; Eltahla AA; Keoshkerian E; Walker MR; Underwood A; Brasher NA; Agapiou D; Lloyd AR; Bull RA, 2019, 'A method for detecting hepatitis C envelope specific memory B cells from multiple genotypes using cocktail E2 tetramers', Journal of Immunological Methods, 472, pp. 65 - 74, http://dx.doi.org/10.1016/j.jim.2019.06.016
2019
Keck ZY; Pierce BG; Lau P; Lu J; Wang Y; Underwood A; Bull RA; Prentoe J; Velázquez-Moctezuma R; Walker MR; Luciani F; Guest JD; Fauvelle C; Baumert TF; Bukh J; Lloyd AR; Foung SKH, 2019, 'Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis c virus infections uncover molecular determinants for E2 targeting and vaccine design', Plos Pathogens, 15, pp. e1007772, http://dx.doi.org/10.1371/journal.ppat.1007772
2019
Underwood AP; Walker MR; Brasher NA; Eltahla AA; Maher L; Luciani F; Lloyd AR; Bull RA, 2018, 'Understanding the determinants of BnAb induction in acute HCV infection', Viruses, 10, pp. 659, http://dx.doi.org/10.3390/v10110659
2018
Rodrigo C; Walker MR; Leung P; Eltahla AA; Grebely J; Dore GJ; Applegate T; Page K; Dwivedi S; Bruneau J; Morris MD; Cox AL; Osburn W; Kim AY; Schinkel J; Shoukry NH; Lauer GM; Maher L; Hellard M; Prins M; Luciani F; Lloyd AR; Bull RA, 2017, 'Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection', Infection Genetics and Evolution, 49, pp. 88 - 96, http://dx.doi.org/10.1016/j.meegid.2017.01.006
2017
Mutanga O; Walker M, 2017, 'Exploration of the academic lives of students with disabilities at South African universities: Lecturers’ perspectives', African Journal of Disability, 6, pp. 316, http://dx.doi.org/10.4102/ajod.v6i0.316
2017
Bull RA; Eltahla AA; Rodrigo C; Koekkoek SM; Walker M; Pirozyan MR; Betz-Stablein B; Toepfer A; Laird M; Oh S; Heiner C; Maher L; Schinkel J; Lloyd AR; Luciani F; Rasoli Pirozyan M, 2016, 'A method for near full-length amplification and sequencing for six hepatitis C virus genotypes', BMC Genomics, 17, pp. 247, http://dx.doi.org/10.1186/s12864-016-2575-8
2016
Walker MR; Li H; Teutsch S; Betz-Stablein B; Luciani F; Lloyd AR; Bull RA; Dolan K; Maher L, 2016, 'Incident hepatitis c virus genotype distribution and multiple infection in australian prisons', Journal of Clinical Microbiology, 54, pp. 1855 - 1861, http://dx.doi.org/10.1128/JCM.00287-16
2016
Bull RA; Leung P; Gaudieri S; Deshpande P; Cameron B; Walker M; Chopra A; Lloyd AR; Luciani F, 2015, 'Transmitted/Founder Viruses Rapidly Escape from CD8 + T Cell Responses in Acute Hepatitis C Virus Infection', Journal of Virology, 89, pp. 5478 - 5490, http://dx.doi.org/10.1128/jvi.03717-14
2015
Albrechtsen A; Grarup N; Li Y; Sparsø T; Tian G; Cao H; Jiang T; Kim SY; Korneliussen T; Li Q; Nie C; Wu R; Skotte L; Morris AP; Ladenvall C; Cauchi S; Stančáková A; Andersen G; Astrup A; Banasik K; Bennett AJ; Bolund L; Charpentier G; Chen Y; Dekker JM; Doney ASF; Dorkhan M; Forsen T; Frayling TM; Groves CJ; Gui Y; Hallmans G; Hattersley AT; He K; Hitman GA; Holmkvist J; Huang S; Jiang H; Jin X; Justesen JM; Kristiansen K; Kuusisto J; Lajer M; Lantieri O; Li W; Liang H; Liao Q; Liu X; Ma T; Ma X; Manijak MP; Marre M; Mokrosiński J; Morris AD; Mu B; Nielsen AA; Nijpels G; Nilsson P; Palmer CNA; Rayner NW; Renström F; Ribel-Madsen R; Robertson N; Rolandsson O; Rossing P; Schwartz TW; Slagboom PE; Sterner M; D.E.S.I.R. Study Group ; Tang M; Tarnow L; the DIAGRAM Consortium ; Tuomi T; van’t Riet E; van Leeuwen N; Varga TV; Vestmar MA; Walker M; Wang B; Wang Y; Wu H; Xi F; Yengo L; Yu C; Zhang X; Zhang J; Zhang Q; Zhang W; Zheng H; Zhou Y; Altshuler D; ‘t Hart LM; Franks PW; Balkau B; Froguel P; McCarthy MI; Laakso M; Groop L; Christensen C; Brandslund I; Lauritzen T; Witte DR; Linneberg A; Jørgensen T; Hansen T; Wang J; Nielsen R; Pedersen O, 2013, 'Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes', Diabetologia, 56, pp. 298 - 310, http://dx.doi.org/10.1007/s00125-012-2756-1
2013
Walker MR; Barfod L, 2022, 'Production of PfEMP1-Specific Human Monoclonal Antibodies from Naturally Immune Individuals', in Methods in Molecular Biology, pp. 407 - 421, http://dx.doi.org/10.1007/978-1-0716-2189-9_30
2022
Walker M; Leung P; Eltahla A; Rodrigo C; Luciani F; Foung S; Lloyd A; Bull R, 2015, 'Understanding the timing, breadth and potency of neutralising antibody responses against transmitted/founders', presented at 11th National Scientific Workshop of the Australian Center for HIV and Hepatitis Virology Research, Hunter Valley, Australia
2015
Leung P; Walker M; Rodrigo C; Eltahla A; Bull R; Lloyd A; Luciani F, 2015, 'Identification of co-evolving mutations of the Hepatitis C virus in the context of immune escape against neutralizing antibody responses using a bioinformatics workflow', presented at 8th Australasian virology society meeting, Hunter Valley, Australia
2015
Walker M; Leung P; Rodrigo C; Eltahla A; Lloyd A; Foung S; Luciani F; Bull R, 2015, 'Characterizing neutralizing antibody responses targeting founder virus in early primary HCV infection with varying disease outcome', presented at International Symposium on Hepatitis C virus and related viruses, Strasbourg, France
2015
Leung P; Walker M; Rodrigo C; Eltahla A; Bull R; Lloyd A; Luciani F, 2015, 'A network approach for the identification of co-evolving mutations in Hepatitis C Virus (HCV) in the context of immune escape against neutralizing antibody responses', presented at COMBINE Student Symposium, Sydney, Australia
2015
Walker MR; Leung P; Keoshkerian E; Pirozyan MR; Lloyd AR; Luciani F; Bull RA, Temporal dynamics of viral fitness and the adaptive immune response in HCV infection, http://dx.doi.org/10.1101/2024.09.07.611784
Dalgaard N; Olsen RW; Adams Y; Mendez BL; Bisholm SAG; Rudbaek JJ; Mousiliou A; Walker MR; Hviid L; Tahar R; Ndam NT; Barfod L; Jensen AR, A monoclonal antibody selectively recognizing PfEMP1 proteins associated with cerebral malaria, http://dx.doi.org/10.21203/rs.3.rs-6252569/v1
Walker M; Underwood A; Raghavan SSR; Bassi M; Björnsson K; Binderup A; Pham L; Ramirez S; Pinholt M; Dagil R; Knudsen A; Idorn M; Søgaard M; Wang K; Salanti A; Bukh J; Barfod L, Novel, broad and potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages, http://dx.doi.org/10.21203/rs.3.rs-3062716/v1

MRFF (CI-D, $1,980,000.00, APP2035199). July 2024.

 

NHMRC Ideas grant (CI-C, $1,143,599.00, APP2020192). January 2023. 

 

UNSW Triple I Seed grant (CI-A, $70,000). July 2024

 

Parse/Ramaciotti single cell grant (CI-A, $10,000). September 2025

 

Career Advancement Fund (CI-A, $10,000). August 2025

 

Australian Centre for HIV and Hepatitis Virology Research Seed funding (CI-A, $10,000). July 2024

 

School of Biomedical (SBMS) Systems Immunology Initiative (SII) seed funding scheme (CI-A, $12,000). July 2023